I'm at 16/43 (stock rear, -2 front).
I had run about 4000 miles since new on a -1 front and it made a big difference and is well worth it. It was a bit of a wheelie monster in lower gears though (all stock powerwise).
I lowered and stretched it (8" extension) when I put in the 16tooth and it never wheelies now.
I would do a -1 front or +3 rear, but not anything more without a stretch, if you want to use the power well. Also, definitely don't do more than my gearing. I'm pretty buzzy/high rpm for street use and still spin the tire at the track in first.
For what its worth...