Hello mate, 2017 saw both McGuinness and Guy Martin crash badly on Honda race bikes.
McGuinness is still having problems with his leg from that crash due to the throttle sticking. The leg injury caused him to pull out of this year's TT with Norton because its not healed well enough.
Guy's Honda had a technical "glitch" or in Yorkshire language that means "a box full of bloody neutrals" which caused his bikes front wheel to hit a kerb and forcing him to dismount at 130 to 140mph on the road course.
Guy quit racing completely after that, although he has capitulated slightly and returned to some racing.